Ambrisentan for treatment of inoperable chronic thromboembolic pulmonary hypertension (CTEPH)
نویسندگان
چکیده
منابع مشابه
Case 1: chronic thromboembolic pulmonary hypertension (CTEPH).
DT Murphy, DM Murphy, JG Murray, SP Gaine Mater Misericordiae University Hospital, Eccles St, Dublin 7
متن کاملBosentan for Treatment of Inoperable Chronic Thromboembolic Pulmonary Hypertension
Methods The BENEFiT (Bosentan Effects in iNopErable Forms of chronIc Thromboembolic pulmonary hypertension) study was a double-blind, randomized, placebo-controlled study in CTEPH including patients with either inoperable CTEPH or persistent/recurrent pulmonary hypertension after PEA ( 6 months after PEA). Independent coprimary end points were change in PVR as a percentage of baseline and chang...
متن کاملBalloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension.
PURPOSE OF REVIEW Chronic thromboembolic pulmonary hypertension (CTEPH), especially when severe in patients unsuited for pulmonary endarterectomy, has a poor prognosis. Balloon pulmonary angioplasty (BPA) is a new catheter-based alternative treatment option for patients with inoperable CTEPH. BPA has not been widely accepted, however, primarily because of possible fatal complications, although ...
متن کاملCatheter-Based Therapy for Inoperable Chronic Thromboembolic Pulmonary Hypertension.
Interventional cardiologists have been innovators in treating all forms of vascular and valvular heart disease in the systemic circulation; however, the pulmonary circulation has not received the same degree of interest from our community. Recent advances in the diagnosis and management of pulmonary vascular diseases and multidisciplinary collaboration among pulmonologists, cardiologists, and s...
متن کاملBosentan therapy for inoperable chronic thromboembolic pulmonary hypertension.
STUDY OBJECTIVES We performed an open-label multicenter study to evaluate the safety and efficacy of the dual endothelin receptor antagonist bosentan in patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH). PATIENTS Nineteen patients with inoperable CTEPH were enrolled. MEASUREMENTS The primary end point was a change in pulmonary vascular resistance (PVR). Secondar...
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ژورنال
عنوان ژورنال: Pulmonary Circulation
سال: 2019
ISSN: 2045-8940,2045-8940
DOI: 10.1177/2045894019846433